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13 13  ~* For details on computation of the electrostatic potential see [[Calculate electrostatic potential>>doc:Collabs.computation-of-protein-association-rates.d.WebHome]].
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15 -~* For details on the similarity computations and pipsa algorithm, see :ref:`el_multipipsa`
15 +~* For details on the similarity computations and [[pipsa algorithm>>doc:Collabs.computation-of-protein-association-rates.Compare a specific region of the electrostatic potentials surrounding a set of protein isoforms with multipipsa.WebHome]].
16 16  
17 17  == Input Data ==
18 18  
19 -In this use case, we use as our input structure a structure of the catalytic domain of the enzyme adenylyl cyclase 5 (AC5), modelled during the work described in |doi_tong|.
19 +In this use case, we use as our input structure a structure of the catalytic domain of the enzyme adenylyl cyclase 5 (AC5), modelled during the work described in [[Tong et al. (2016)>>https://doi.org/10.1002/prot.25167]]
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21 21  The structures of the AC isoforms were created via homology modelling using the same template. The region where there are significant structural differences between the isoforms is in a flexible loop region that was not defined in the template structure. There are also variations in sequence length across AC isoforms in this region.
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