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Last modified by richtesn on 2023/06/15 15:51

From version 3.1
edited by richtesn
on 2021/06/14 11:11
Change comment: There is no comment for this version
To version 4.1
edited by richtesn
on 2021/06/14 11:11
Change comment: There is no comment for this version

Summary

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1 -Compare a specific region of the electrostatic potentials surrounding a set of protein isoforms with multipipsa
1 +2.3 Compare a specific region of the electrostatic potentials surrounding a set of protein isoforms with multipipsa
Content
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16 16  
17 17  In this use case, we use as our input structure a structure of the catalytic domain of the enzyme adenylyl cyclase 5 (AC5), modelled during the work described in |doi_tong|.  The structures of the AC isoforms were created via homology modelling using the same template. The region where there are significant structural differences between the isoforms is in a flexible loop region that was not defined in the template structure. There are also variations in sequence length across AC isoforms in this region.
18 18  
19 -.. |doi_tong| raw:: html
19 +.. |doi_tong| raw:: html 
20 20  
21 21  
22 22   <a href="https:~/~/doi.org/10.1002/prot.25167" target="_blank">Tong et al (2016)</a>