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* ((( ==== **[[Intermediate >>||anchor = "HIntermediate-1"]]** ==== ))) |
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-* ((( ==== **[[Advanced >>||anchor = "HAdvanced-1"]]** ==== ))) |
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=== **Beginner** === |
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=== [[Creating a simple cell optimisation>>https://github.com/BlueBrain/BluePyOpt/blob/master/examples/simplecell/simplecell.ipynb||rel=" noopener noreferrer" target="_blank"]] === |
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**Level**: intermediate(%%) **Type**: interactive tutorial |
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In this notebook we demonstrate how to fit the parameters of the Tsodyks-Markram model to a given in vitro somatic recording. The in vitro trace used here shows a typical L5TTPC-L5TTPC depressing connection, kindly provided by Rodrigo Perin (EPFL). |
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-=== [[Optimization of burst and tonic firing in thalamo-cortical neurons>>https://github.com/BlueBrain/BluePyOpt/blob/master/examples/thalamocortical-cell/thalamocortical-cell_opt.ipynb||rel=" noopener noreferrer" target="_blank"]] === |
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-**Level**: intermediate(%%) **Type**: interactive tutorial |
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-In this tutorial we will go over how to set up the cell model and the cell evaluator, run an optimisation and how to analyse optimisation results. |
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-=== **Advanced** === |
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-=== [[Optimisation of a Neocortical Layer 5 Pyramidal Cell>>https://github.com/BlueBrain/BluePyOpt/blob/master/examples/l5pc/L5PC.ipynb||rel=" noopener noreferrer" target="_blank"]] === |
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-**Level**: advanced(%%) **Type**: interactive tutorial |
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-This notebook shows you how to optimise the maximal conductance of Neocortical Layer 5 Pyramidal Cell as used in Markram et al. 2015. |
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-=== [[Optimisation of a Neocortical Layer 5 Pyramidal Cell in Arbor>>https://github.com/BlueBrain/BluePyOpt/blob/master/examples/l5pc/L5PC_arbor.ipynb||rel=" noopener noreferrer" target="_blank"]] === |
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-**Level**: advanced(%%) **Type**: interactive tutorial |
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-This notebook shows you how to optimise the maximal conductance of Neocortical Layer 5 Pyramidal Cell as used in Markram et al. 2015 using Arbor as the simulator. |
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-=== [[Simulating optimized cell models in Arbor and cross-validation with Neuron>>https://github.com/BlueBrain/BluePyOpt/blob/master/examples/l5pc/l5pc_validate_neuron_arbor.ipynb||rel=" noopener noreferrer" target="_blank"]] === |
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-**Level**: advanced(%%) **Type**: interactive tutorial |
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-This notebook demonstrates how to run a simulation of a simple single compartmental cell with fixed/optimized parameters in Arbor. We follow the standard BluePyOpt flow of setting up an electrophysiological experiment and export the cell model to a mixed JSON/ACC-format. We then cross-validate voltage traces obtained with Arbor with those from a Neuron simulation. |
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