Wiki source code of Mesocircuit

Version 7.2 by senk on 2020/04/30 18:41

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7.2	5	= The cortical mesocircuit model =
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	7	A layered network model covering 4x4 mm² of cortical surface area
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	17	= Overview =
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7.2	19	The cortical mesocircuit model is a lateral extension of the microcircuit model published by [[Potjans & Diesmann (2014)>>https://doi.org/10.1093/cercor/bhs358]].
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7.2	21	[[image:mesocircuit_sketch.png\|\|height="277" width="340"]]
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	33	Like the microcircuit, the mesocircuit represents four layers of cortex, L2/3, L4, L5, and L6, each consisting of a population of excitatory neurons and a population of inhibitory neurons. External input can be provided by a thalamic population TC.
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	35	The mesocircuit is a spatially structured network model covering 4x4 mm² of cortical surface area which is similar in size to multi-electrode arrays in use today.
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	37	The neurons of each population are assigned random positions in 2-dimensional layers and they are connected with distance-dependent connection probabilities and conduction delays.
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	39	The densities of neurons and local synapses in the network are assumed to be realistic, amounting to ~~1.2 million neurons and ~~5.5 billion synapses.
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	41	The model accounts for both spiking activity simulated with [[NEST>>https://www.nest-simulator.org]] and local-field potentials relying on [[LFPy>>https://LFPy.rtfd.io]].
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	44	= Status of model development =
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	46	The mesocircuit is still under development and the neither the code nor a peer-reviewed manuscript have been published, yet.
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	48	To date, only a [[preprint>>https://arxiv.org/abs/1805.10235]] with detailed model documentation and preliminary results is available on ArXiv.
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	50	The Drive of this Collab provides access to a [[recent version of the model implementation>>https://wiki.ebrains.eu/bin/view/Collabs/mesocircuit/Drive]].
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	52	The development of the mesocircuit model belongs to task "T4.2.1 - Spiking mesoscale cortical models with spatial organization" and constitutes the [[component C2418>>https://plus.humanbrainproject.eu/components/2418]].
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