Changes for page Neurodiagnoses

Last modified by manuelmenendez on 2025/03/03 22:46
From version 12.1
edited by manuelmenendez
on 2025/01/27 23:54
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To version 21.1
edited by manuelmenendez
on 2025/01/28 00:30
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2 2  (((
3 3  (% class="container" %)
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5 -= //A new tridimensional diagnostic framework for CNS conditions// =
5 += //A new tridimensional diagnostic framework for neurodegenerative diseases// =
6 6  
7 -This project is focused on developing a novel nosological and diagnostic framework for neurological diseases by using advanced AI techniques and integrating data from neuroimaging, biomarkers, and biomedical ontologies.
7 +This project is focused on developing a novel nosological and diagnostic framework for neurodegenerative diseases by using advanced AI techniques and integrating data from neuroimaging, biomarkers, and biomedical ontologies.
8 8  We aim to create a structured, interpretable, and scalable diagnostic tool.
9 9  )))
10 10  )))
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17 17  
18 18  == **Overview** ==
19 19  
20 -The //Tridimensional Diagnostic Framework// redefines how neurodegenerative diseases (NDDs) are classified by focusing on:
20 +The //Tridimensional Diagnostic Framework// redefines how neurodegenerative diseases (NDD) are classified by focusing on:
21 21  
22 -* **Axis 1**: Etiology (genetic/sporadic and environmental factors).
23 -* **Axis 2**: Molecular Markers (biomarkers and proteinopathies).
22 +* **Axis 1**: Etiology (genetic or other causes of diseases).
23 +* **Axis 2**: Molecular Markers (biomarkers).
24 24  * **Axis 3**: Neuroanatomoclinical correlations (linking clinical symptoms to structural changes in the nervous system).
25 25  
26 +[[Neurodegenerative diseases can be studied and classified in a tridimensional scheme with three axes: anatomic–clinical, molecular, and etiologic. CSF, cerebrospinal fluid; FDG, fluorodeoxyglucose; MRI, magnetic resonance imaging; PET, positron emission tomography.>>image:tridimensional.png||alt="tridimensional view of neurodegenerative diseases"]]
27 +
28 +
26 26  This methodology enables:
27 27  
28 28  * Greater precision in diagnosis.
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90 90  * `/code`: Machine learning pipelines and scripts.
91 91  * `/data`: Sample datasets for testing.
92 92  * `/outputs`: Generated models, visualizations, and reports.
96 +* [[Methodology>>url:https://wiki.ebrains.eu/bin/view/Collabs/neurodiagnoses/Methodology/]]
97 +* [[Results>>url:https://wiki.ebrains.eu/bin/view/Collabs/neurodiagnoses/Results/]]
93 93  )))
94 94  )))
tridimensional.png
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1 +XWiki.manuelmenendez
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1 -No
1 +Yes