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5		-= //A new tridimensional diagnostic framework for CNS conditions// =
	5	+= //A new tridimensional diagnostic framework for neurodegenerative diseases// =
6	6
7		-This project is focused on developing a novel nosological and diagnostic framework for neurological diseases by using advanced AI techniques and integrating data from neuroimaging, biomarkers, and biomedical ontologies.
	7	+This project is focused on developing a novel nosological and diagnostic framework for neurodegenerative diseases by using advanced AI techniques and integrating data from neuroimaging, biomarkers, and biomedical ontologies.
8	8	We aim to create a structured, interpretable, and scalable diagnostic tool.
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17	17
18	18	== **Overview** ==
19	19
20		-The //Tridimensional Diagnostic Framework// redefines how neurodegenerative diseases (NDDs) are classified by focusing on:
	20	+The //Tridimensional Diagnostic Framework// redefines how neurodegenerative diseases (NDD) are classified by focusing on:
21	21
22		-* **Axis 1**: Etiology (genetic/sporadic and environmental factors).
23		-* **Axis 2**: Molecular Markers (biomarkers and proteinopathies).
	22	+* **Axis 1**: Etiology (genetic or other causes of diseases).
	23	+* **Axis 2**: Molecular Markers (biomarkers).
24	24	* **Axis 3**: Neuroanatomoclinical correlations (linking clinical symptoms to structural changes in the nervous system).
25	25
	26	+[[Neurodegenerative diseases can be studied and classified in a tridimensional scheme with three axes: anatomic–clinical, molecular, and etiologic. CSF, cerebrospinal fluid; FDG, fluorodeoxyglucose; MRI, magnetic resonance imaging; PET, positron emission tomography.>>image:tridimensional.png||alt="tridimensional view of neurodegenerative diseases"]]
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26	26	This methodology enables:
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28	28	* Greater precision in diagnosis.
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90	90	* `/code`: Machine learning pipelines and scripts.
91	91	* `/data`: Sample datasets for testing.
92	92	* `/outputs`: Generated models, visualizations, and reports.
	96	+* [[Methodology>>url:https://wiki.ebrains.eu/bin/view/Collabs/neurodiagnoses/Methodology/]]
	97	+* [[Results>>url:https://wiki.ebrains.eu/bin/view/Collabs/neurodiagnoses/Results/]]
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tridimensional.png

Author

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	1	+XWiki.manuelmenendez

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	1	+149.8 KB

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