Changes for page Neurodiagnoses
Last modified by manuelmenendez on 2025/03/03 22:46
From version 18.1
edited by manuelmenendez
on 2025/01/28 00:02
on 2025/01/28 00:02
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To version 7.2
edited by manuelmenendez
on 2025/01/27 23:22
on 2025/01/27 23:22
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... ... @@ -2,7 +2,7 @@ 2 2 ((( 3 3 (% class="container" %) 4 4 ((( 5 -= //A new tridimensional diagnostic framework for neurodegenerativediseases// =5 += //A new tridimensional diagnostic framework for CNS conditions// = 6 6 7 7 This project is focused on developing a novel nosological and diagnostic framework for neurological diseases by using advanced AI techniques and integrating data from neuroimaging, biomarkers, and biomedical ontologies. 8 8 We aim to create a structured, interpretable, and scalable diagnostic tool. ... ... @@ -15,17 +15,14 @@ 15 15 ((( 16 16 = What is this about and what can I find here? = 17 17 18 -== **Overview** == 18 +==== **Overview** ==== 19 19 20 -The //Tridimensional Diagnostic Framework// redefines how neurodegenerative diseases (NDD) are classified by focusing on: 20 +The //Tridimensional Diagnostic Framework// redefines how neurodegenerative diseases (NDDs) are classified by focusing on: 21 21 22 -* **Axis 1**: Etiology (genetic othercausesofdiseases).23 -* **Axis 2**: Molecular Markers (biomarkers). 22 +* **Axis 1**: Etiology (genetic/sporadic and environmental factors). 23 +* **Axis 2**: Molecular Markers (biomarkers and proteinopathies). 24 24 * **Axis 3**: Neuroanatomoclinical correlations (linking clinical symptoms to structural changes in the nervous system). 25 25 26 -[[Neurodegenerative diseases can be studied and classified in a tridimensional scheme with three axes: anatomic–clinical, molecular, and etiologic. CSF, cerebrospinal fluid; FDG, fluorodeoxyglucose; MRI, magnetic resonance imaging; PET, positron emission tomography.>>image:tridimensional.png||alt="tridimensional view of neurodegenerative diseases"]] 27 - 28 - 29 29 This methodology enables: 30 30 31 31 * Greater precision in diagnosis. ... ... @@ -32,7 +32,7 @@ 32 32 * Integration of incomplete datasets using AI-driven probabilistic modeling. 33 33 * Stratification of patients for personalized treatment. 34 34 35 -== **Diagnostic Axes** == 32 +==== **Diagnostic Axes** ==== 36 36 37 37 * ((( 38 38 **Axis 1: Etiology** ... ... @@ -56,7 +56,7 @@ 56 56 * //Tests//: MRI volumetrics, FDG-PET, neuropsychological evaluations. 57 57 ))) 58 58 59 -== **Applications** == 56 +==== **Applications** ==== 60 60 61 61 This system enhances: 62 62 ... ... @@ -67,13 +67,13 @@ 67 67 68 68 We welcome contributions from the global community. Let’s build the future of neurological diagnostics together! 69 69 70 -== How to Contribute == 67 +== How to Contribute: == 71 71 72 72 * Access the `/docs` folder for guidelines. 73 73 * Use `/code` for the latest AI pipelines. 74 74 * Share feedback and ideas in the wiki discussion pages. 75 75 76 -== Key Objectives == 73 +== Key Objectives: == 77 77 78 78 * Develop interpretable AI models for diagnosis and progression tracking. 79 79 * Integrate data from Human Phenotype Ontology (HPO), Gene Ontology (GO), and other biomedical resources. ... ... @@ -87,7 +87,7 @@ 87 87 {{toc/}} 88 88 {{/box}} 89 89 90 -== Main contents == 87 +== Main contents: == 91 91 92 92 * `/docs`: Documentation and contribution guidelines. 93 93 * `/code`: Machine learning pipelines and scripts.
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