Changes for page Neurodiagnoses
Last modified by manuelmenendez on 2025/03/03 22:46
From version 9.1
edited by manuelmenendez
on 2025/01/27 23:23
on 2025/01/27 23:23
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To version 16.1
edited by manuelmenendez
on 2025/01/28 00:00
on 2025/01/28 00:00
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... ... @@ -17,12 +17,15 @@ 17 17 18 18 == **Overview** == 19 19 20 -The //Tridimensional Diagnostic Framework// redefines how neurodegenerativediseases(NDDs)are classified by focusing on:20 +The //Tridimensional Diagnostic Framework// redefines how CNS conditions are classified by focusing on: 21 21 22 -* **Axis 1**: Etiology (genetic /sporadicand environmentalfactors).23 -* **Axis 2**: Molecular Markers (biomarkers and proteinopathies).22 +* **Axis 1**: Etiology (genetic or other causes of diseases). 23 +* **Axis 2**: Molecular Markers (biomarkers). 24 24 * **Axis 3**: Neuroanatomoclinical correlations (linking clinical symptoms to structural changes in the nervous system). 25 25 26 +[[Neurodegenerative diseases can be studied and classified in a tridimensional scheme with three axes: anatomic–clinical, molecular, and etiologic. CSF, cerebrospinal fluid; FDG, fluorodeoxyglucose; MRI, magnetic resonance imaging; PET, positron emission tomography.>>image:tridimensional.png||alt="tridimensional view of neurodegenerative diseases"]] 27 + 28 + 26 26 This methodology enables: 27 27 28 28 * Greater precision in diagnosis. ... ... @@ -64,13 +64,13 @@ 64 64 65 65 We welcome contributions from the global community. Let’s build the future of neurological diagnostics together! 66 66 67 -== How to Contribute :==70 +== How to Contribute == 68 68 69 69 * Access the `/docs` folder for guidelines. 70 70 * Use `/code` for the latest AI pipelines. 71 71 * Share feedback and ideas in the wiki discussion pages. 72 72 73 -== Key Objectives :==76 +== Key Objectives == 74 74 75 75 * Develop interpretable AI models for diagnosis and progression tracking. 76 76 * Integrate data from Human Phenotype Ontology (HPO), Gene Ontology (GO), and other biomedical resources. ... ... @@ -84,7 +84,7 @@ 84 84 {{toc/}} 85 85 {{/box}} 86 86 87 -== Main contents :==90 +== Main contents == 88 88 89 89 * `/docs`: Documentation and contribution guidelines. 90 90 * `/code`: Machine learning pipelines and scripts.
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