Changes for page Neurodiagnoses

Last modified by manuelmenendez on 2025/03/03 22:46
From version 9.1
edited by manuelmenendez
on 2025/01/27 23:23
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To version 16.1
edited by manuelmenendez
on 2025/01/28 00:00
Change comment: There is no comment for this version

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17 17  
18 18  == **Overview** ==
19 19  
20 -The //Tridimensional Diagnostic Framework// redefines how neurodegenerative diseases (NDDs) are classified by focusing on:
20 +The //Tridimensional Diagnostic Framework// redefines how CNS conditions are classified by focusing on:
21 21  
22 -* **Axis 1**: Etiology (genetic/sporadic and environmental factors).
23 -* **Axis 2**: Molecular Markers (biomarkers and proteinopathies).
22 +* **Axis 1**: Etiology (genetic or other causes of diseases).
23 +* **Axis 2**: Molecular Markers (biomarkers).
24 24  * **Axis 3**: Neuroanatomoclinical correlations (linking clinical symptoms to structural changes in the nervous system).
25 25  
26 +[[Neurodegenerative diseases can be studied and classified in a tridimensional scheme with three axes: anatomic–clinical, molecular, and etiologic. CSF, cerebrospinal fluid; FDG, fluorodeoxyglucose; MRI, magnetic resonance imaging; PET, positron emission tomography.>>image:tridimensional.png||alt="tridimensional view of neurodegenerative diseases"]]
27 +
28 +
26 26  This methodology enables:
27 27  
28 28  * Greater precision in diagnosis.
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64 64  
65 65  We welcome contributions from the global community. Let’s build the future of neurological diagnostics together!
66 66  
67 -== How to Contribute: ==
70 +== How to Contribute ==
68 68  
69 69  * Access the `/docs` folder for guidelines.
70 70  * Use `/code` for the latest AI pipelines.
71 71  * Share feedback and ideas in the wiki discussion pages.
72 72  
73 -== Key Objectives: ==
76 +== Key Objectives ==
74 74  
75 75  * Develop interpretable AI models for diagnosis and progression tracking.
76 76  * Integrate data from Human Phenotype Ontology (HPO), Gene Ontology (GO), and other biomedical resources.
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84 84  {{toc/}}
85 85  {{/box}}
86 86  
87 -== Main contents: ==
90 +== Main contents ==
88 88  
89 89  * `/docs`: Documentation and contribution guidelines.
90 90  * `/code`: Machine learning pipelines and scripts.
tridimensional.png
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