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Last modified by puchades on 2022/11/02 10:16
From version 2.1
edited by sharoncy
on 2020/03/09 13:03
Change comment: There is no comment for this version
To version 31.1
edited by puchades
on 2020/03/12 16:55
Change comment: There is no comment for this version

Summary

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6 +The QUINT workflow enables the quantification and spatial analysis of labelled features in histological images of rodent brain sections based on reference atlases of the brain. It utilises three open-source software:
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8 +1. [[(% style="color:#2980b9" %)//ilastik//>>doc:.3\. Image segmentation with ilastik.WebHome]](%%) allows the extraction of labelled features such as cells by segmentation.
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12 +In combination, the tools facilitate semi-automated quantification, eliminating the need for more time consuming methods such as stereological analysis with manual delineation of brain regions.
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55 +* As the quantifications are performed in regions defined by a reference atlas, the region definitions are standardized, allowing comparisons of data from different laboratories.
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57 +==== (% style="color:#c0392b" %)**References**(%%) ====
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59 +Yates SC et al. 2019. QUINT: Workflow for Quantification and Spatial Analysis of Features in Histological Images From Rodent Brain. Front. Neuroinform. 13:75. doi: 10.3389/fninf.2019.00075
60 +
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