Changes for page QUINT: Workflow for Quantification and Spatial Analysis of Features in Histological Images From Rodent Brain
Last modified by puchades on 2022/11/02 10:16
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... ... @@ -1,13 +1,11 @@ 1 -[[image:QUINT_workflow_Plaques.png||style="float:left"]] 1 +(% style="text-align:center" %) 2 +[[image:QUINT_workflow_pic.png||height="391" width="1003"]] 2 2 3 -== (% style="color:#c0392b" %)**Description**(%%) == 4 4 5 - **TheQUINTworkflow enablesan atlas based analysisof extractedfeaturesfrom histologicalimageections from the rodent brain using 3D reference atlases.**5 +== (% style="color:#c0392b" %)**Workflow Description**(%%) == 6 6 7 - **Examplesofuseare:cellcountingand spatialdistributions;determination ofprojectionareas inconnectivity experiments;exploration ofpathologicalhallmarksbraindiseasemodels. Integrationof variousdatato the samereferencespace enablesnewexplorationstrategiesandre-useofexperimentaldata.**7 +The QUINT workflow facilitates the quantification and spatial analysis of labelled features in images of histological sections from the rodent brain using 3D reference atlases. The workflow is built on the following open access software: 8 8 9 -The workflow is built on the following open access software: 10 - 11 11 * [[(% style="color:#2980b9" %)//ilastik//>>doc:.3\. Image segmentation with ilastik.WebHome]](%%) allows the extraction of labelled features such as cells, using machine learning image segmentation. 12 12 * [[(% style="color:#2980b9" %)//QuickNII//>>doc:.Image registration to reference atlas using QuickNII.WebHome]](%%) generates custom-angle slices from volumetric brain atlases to match the proportions and cutting plane of histological sections. 13 13 * //[[(% style="color:#3498db" %)VisuAlign>>doc:.Image registration to reference atlas using QuickNII.WebHome]]//(%%) is then used for nonlinear alignment of the reference atlas slice to the section image..