Changes for page SGA3 D1.2 Showcase 1

Last modified by fousekjan on 2022/07/04 18:31
From version 10.1
edited by fousekjan
on 2022/01/03 08:59
Change comment: Uploaded new attachment "image-20220103095948-1.png", version {1}
To version 11.1
edited by fousekjan
on 2022/01/03 09:08
Change comment: Uploaded new attachment "image-20220103100841-2.png", version {1}

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23 23  
24 24  == Regional variability data ==
25 25  
26 -The first step of the regional variability workflow loads the data from the Knowledge Graph and defines the regional bias on the model. In this case we require: 1) structural connectivity matrices, 2) GABA and AMPA receptor densities at each region, and 3) empirical resting-state fMRI data for fitting and validation of the simulations. The three datasets shall be characterised in the same parcellation. The notebook can be found here: [[regional_variability/notebooks/1_data_setup.ipynb>>https://lab.ch.ebrains.eu/user-redirect/lab/tree/shared/SGA3%20D1.2%20Showcase%201/regional_variability/notebooks/1_data_setup.ipynb]]
26 +The first step of the regional variability workflow loads the data from the Knowledge Graph and defines the regional bias on the model. In this case we require: 1) structural connectivity matrices, 2) GABA and AMPA receptor densities at each region, and 3) empirical resting-state fMRI data for fitting and validation of the simulations. The three datasets shall be characterised in the same parcellation.
27 27  
28 +Link to the notebook:
29 +
30 +* [[regional_variability/notebooks/1_data_setup.ipynb>>https://lab.ch.ebrains.eu/user-redirect/lab/tree/shared/SGA3%20D1.2%20Showcase%201/regional_variability/notebooks/1_data_setup.ipynb]]
31 +
28 28  (% style="text-align:center" %)
29 29  [[image:image-20220103095424-1.png]]
30 30  
31 -
35 +== Fitting model parameters for models with regional bias ==
36 +
37 +A series of simulations of the whole-brain network model is launched in the EBRAINS HPC facilities in order to identify the optimal model parameters leading to simulated resting-state brain activity that best resembles the empirically observed activity.
38 +
39 +Link to the notebook:
40 +
41 +* [[regional_variability/notebooks/2_parameter_swep_proto.ipynb>>https://lab.ch.ebrains.eu/user-redirect/lab/tree/shared/SGA3%20D1.2%20Showcase%201/regional_variability/notebooks/2_parameter_swep_proto.ipynb]]
42 +
43 +[[image:image-20220103095948-1.png]]
32 32  )))
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