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1		-XWiki.fousekjan
	1	+XWiki.gorkazl

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14	14	(((
15	15	The Showcase is implemented as a series of interactive Jupyter notebooks covering the individual logical steps and can be accessed in a dedicated public EBRAINS collab.
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	17	+The EBRAINS collab is a virtual environment that interlinks the Drive, Bucket, Wiki, and Lab services. The Drive provides storage for small files. It contains the notebooks and all the supporting code. The Bucket is a storage service for larger files. It holds the pre-computed results from the extensive parameter sweeps and model optimizations to allow skipping the computationally demanding steps. The documentation of the showcase implementation is collected in the Wiki. The Lab service is an instance of JupyterLab—an interactive computing environment where the notebooks can be run and worked with.
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18		-The EBRAINS collab consists of interlinked Drive, Bucket, Wiki, and Lab. The Drive provides small file storage and contains the notebooks and all supporting code. The Bucket is a large file storage service and holds the pre-computed results of the extensive parameter sweeps and model optimizations to allow skipping the computationally demanding steps. The documentation of the showcase implementation is collected in the Wiki. The Lab service is an instance of JupyterLab—an interactive computing environment where the notebooks can be run and worked with.
	19	+The Jupyter notebooks in this collab will load all required Python modules including Siibra and The Virtual Brain, and the interfaces for launching the computationally demanding parts in the HPC infrastructure.
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	21	+Running the notebooks requires an EBRANS account with permissions to access the Lab and programmatic access to the Knowledge Graph API. In addition, to interact with the HPC infrastructure, the user needs access to an active allocation on the corresponding FENIX site.
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21		-The notebooks in this collab will load all required Python modules including Siibra and The Virtual Brain, and the interfaces for launching the computationally demanding parts in the HPC infrastructure. Running the notebooks requires an EBRANS account with permissions to access the Lab and the Knowledge Graph API. In addition, to be able to interact with the HPC infrastructure, the user has to have access to an active allocation on the corresponding FENIX site.
	23	+== Simulation of resting-state activity ==
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23		-== Simulation of resting state ==
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25	25	The fist notebook in the inter-individual variability workflow explores the resting-state simulation for a subject of the 1000BRAINS dataset. Functional data are simulated by means of a brain network model implemented in TVB, which is an ensemble of neural mass models linked via the weights of the structural connectivity (SC) matrix. Following topics are covered:
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27		-1. The neural mass model by Montbrio, Pazo and Roxin
28		-1. Construction of the TVB model for a particular subject
29		-1. Dynamics of the model, and execution of a parameter study
30		-1. Summary of the simulation results for the whole cohort
	27	+1. The neural mass model by Montbrio, Pazo and Roxin.
	28	+1. Construction of the TVB model for a particular subject.
	29	+1. Dynamics of the model, and execution of a parameter study.
	30	+1. Summary of the simulation results for the whole cohort.
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32	32	Link to the notebook:
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40	40	The second steps shows the investigation of virtual ageing trajectory for each subject. In this context, we are going to show
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42		-1. What we mean by virtual ageing and what is the empirical basis to investigate this approach
43		-1. How we can virtually age a subject using whole-brain modelling
44		-1. How the increase structure-function relationship relates to virtual ageing
	42	+1. What we mean by virtual ageing and what is the empirical basis to investigate this approach.
	43	+1. How we can virtually age a subject using whole-brain modelling.
	44	+1. How the increase structure-function relationship relates to virtual ageing.
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46	46	Link to the notebook:
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