Changes for page SGA3 D1.2 Showcase 1
Last modified by fousekjan on 2022/07/04 18:31
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... ... @@ -61,7 +61,7 @@ 61 61 62 62 == Regional variability data == 63 63 64 -The first step of the regional variability workflow load sthe data from the Knowledge Graphanddefinesthe regional bias on the model. In this case we require:64 +The first step of the regional variability workflow consists in loading the data from the Knowledge Graph, including the regional bias on the model. In this case we require: 65 65 66 66 1. Structural connectivity matrices, 67 67 1. GABA and AMPA receptor densities for each brain region, and ... ... @@ -76,7 +76,7 @@ 76 76 77 77 == Fitting model parameters for models with regional bias == 78 78 79 -A series of simulations of the whole-brain network model are launched in the EBRAINS HPC facilities in order to identify the optimal model parameters leading to simulated resting-state brain activity that best resembles the empirically observed activity. 79 +A series of simulations of the whole-brain network model are launched in the EBRAINS HPC facilities in order to identify the optimal model parameters leading to simulated resting-state brain activity that best resembles the empirically observed activity. In this branch of the showcase, brain regions are simulated using the Balanced Excitation-Inhibition model which allows to tune the E-I balance for every region individually, according to the empirically observed GABA and AMPA neuroreceptor densities. 80 80 81 81 Link to the notebook: 82 82
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