Changes for page SGA3 D1.5 Showcase 1

Last modified by gorkazl on 2023/11/13 14:27
From version 13.1
edited by gorkazl
on 2023/10/09 17:44
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To version 13.2
edited by gorkazl
on 2023/10/09 17:46
Change comment: There is no comment for this version

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89 89  1. GABAa and AMPA receptor densities for each brain region, and
90 90  1. empirical resting-state fMRI data for fitting and validation of the simulations.
91 91  
92 -The three datasets shall be characterised in the same parcellation. Link to the notebook:
92 +The three datasets are characterised in the same parcellation. Link to the notebook:
93 93  
94 94  * [[regional_variability/notebooks/1_load_data.ipynb>>https://lab.ch.ebrains.eu/hub/user-redirect/lab/tree/shared/SGA3%20D1.2%20Showcase%201/regional_variability/notebooks/1_load_data.ipynb]]
95 95  
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96 96  (% style="text-align:center" %)
97 97  [[image:download - 2022-02-10T130815.902.png||alt="region-wise gene expression heterogeneity"]]
98 98  
99 -=== Fitting model parameters for models with regional bias ===
99 +=== Fitting model parameters with regional bias ===
100 100  
101 101  A series of simulations of the whole-brain network model are launched in the EBRAINS HPC facilities in order to identify the optimal model parameters leading to simulated resting-state brain activity that best resembles the empirically observed activity. In this branch of the showcase, brain regions are simulated using the mean-field AdEx population model; specifically modified to account for the regional densities of GABAa and AMPA neuroreceptors. See the details following document.
102 102