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- Slow waves form expanding, memory-rich mesostates steered by local excitability in fading anesthesia
- Summary
- Introduction
- Results:
- Lightening up of anesthesia increases frequency and complexity of slow waves
- Modes of propagation increase in number and speed as anesthesia fades out
- Wavefronts are shaped by previous waves differently across anesthesia levels
- Leading and following assemblies differentially contribute to the rise of complexity
- Changes in local excitability explain the increase of slow-wave complexity
- Anesthesia fading out induces increasing fluctuations of SWA features
- Discussion
- Switch of global brain state associated with anesthesia
- Role of subcortical regions in the slow-wave anti-correlation
- Relationship between slow waves and EEG microstates
- STAR Methods
- Animals
- Surgical procedures
- Electrophysiological recordings
- Data analysis and statistics
- MUA estimate and detection of the state transitions
- Extraction of the wave entropy index (WEI)