Building personalized brain network models with TVB
Spase Petkoski, Damien Depannemaecker and Pierpaolo Sorrentino
What can I find here?
- A current topic in system neuroscience literature is the presence of brain activity in the absence of a task condition. These task-negative, spontaneous fluctuations occur in the so-called rest state, and a recurring theme of these fluctuations is that they have a network structure. Because TVB uses the structural connectivity of the brain as the backbone for simulating spontaneous activity, resting state activity and its network structure is a prime candidate for modeling in TVB.
Other tutorials
In addition to these noptebooks, we also refer to the readers to the collab for the Showcase 1 of HBP: "Degeneracy in neuroscience - when is Big Data big enough"
https://wiki.ebrains.eu/bin/view/Collabs/sga3-d1-5-showcase-1/
References
Sanz-Leon P, Knock SA, Spiegler A, Jirsa VK. Mathematical framework for large-scale brain network modeling in The Virtual Brain. Neuroimage. 2015 May 1;111:385-430.
Schirner M, Domide L, Perdikis D, Triebkorn P, Stefanovski L, Pai R, Prodan P, Valean B, Palmer J, Langford C, Blickensdörfer A. Brain simulation as a cloud service: The Virtual Brain on EBRAINS. NeuroImage. 2022 May 1;251:118973.
Lavanga M, Stumme J, Yalcinkaya BH, Fousek J, Jockwitz C, Sheheitli H, Bittner N, Hashemi M, Petkoski S, Caspers S, Jirsa V. The virtual aging brain: Causal inference supports interhemispheric dedifferentiation in healthy aging. NeuroImage. 2023 Dec 1;283:120403.
Wang HE, Triebkorn P, Breyton M, Dollomaja B, Lemarechal JD, Petkoski S, Sorrentino P, Depannemaecker D, Hashemi M, Jirsa VK. Virtual brain twins: from basic neuroscience to clinical use. National Science Review. 2024 May;11(5):nwae079.