Changes for page Mesocircuit

Last modified by senk on 2022/05/23 22:36
From version 7.2
edited by senk
on 2020/04/30 18:41
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To version 2.1
edited by terhorst
on 2020/04/29 14:00
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5 -= **The cortical mesocircuit model** =
5 += My Collab's Extended Title =
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7 -A layered network model covering 4x4 mm² of cortical surface area
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17 -= Overview =
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19 -The cortical mesocircuit model is a lateral extension of the microcircuit model published by [[Potjans & Diesmann (2014)>>https://doi.org/10.1093/cercor/bhs358]].
21 += Who has access? =
20 20  
21 -[[image:mesocircuit_sketch.png||height="277" width="340"]]
23 +Describe the audience of this collab.
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26 26  {{box title="**Contents**"}}
27 27  {{toc/}}
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33 -Like the microcircuit, the mesocircuit represents four layers of cortex, L2/3, L4, L5, and L6, each consisting of a population of excitatory neurons and a population of inhibitory neurons. External input can be provided by a thalamic population TC.
34 -
35 -The mesocircuit is a spatially structured network model covering 4x4 mm² of cortical surface area which is similar in size to multi-electrode arrays in use today.
36 -
37 -The neurons of each population are assigned random positions in 2-dimensional layers and they are connected with distance-dependent connection probabilities and conduction delays.
38 -
39 -The densities of neurons and local synapses in the network are assumed to be realistic, amounting to ~~1.2 million neurons and ~~5.5 billion synapses.
40 -
41 -The model accounts for both spiking activity simulated with [[NEST>>https://www.nest-simulator.org]] and local-field potentials relying on [[LFPy>>https://LFPy.rtfd.io]].
42 -
43 -(% class="row" id="HStatusofmodeldevelopment" %)
44 -= Status of model development =
45 -
46 -The mesocircuit is still under development and the neither the code nor a peer-reviewed manuscript have been published, yet.
47 -
48 -To date, only a [[preprint>>https://arxiv.org/abs/1805.10235]] with detailed model documentation and preliminary results is available on ArXiv.
49 -
50 -The Drive of this Collab provides access to a [[recent version of the model implementation>>https://wiki.ebrains.eu/bin/view/Collabs/mesocircuit/Drive]].
51 -
52 -The development of the mesocircuit model belongs to task "T4.2.1 - Spiking mesoscale cortical models with spatial organization" and constitutes the [[component C2418>>https://plus.humanbrainproject.eu/components/2418]].
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53 53  )))
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mesocircuit_sketch.png
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Mesocircuit