Changes for page Mesocircuit

Last modified by senk on 2022/05/23 22:36
From version 8.1
edited by senk
on 2020/04/30 18:43
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To version 1.1
edited by terhorst
on 2020/04/29 14:00
Change comment: Collab created through API

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5 -= **The cortical mesocircuit model** =
5 += My Collab's Extended Title =
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7 -A layered network model covering 4x4 mm² of cortical surface area
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17 -= Overview =
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19 -The cortical mesocircuit model is a lateral extension of the microcircuit model published by [[Potjans & Diesmann (2014)>>https://doi.org/10.1093/cercor/bhs358]].
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22 -[[image:mesocircuit_sketch.png||height="333" width="500"]]
23 +Describe the audience of this collab.
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27 27  {{box title="**Contents**"}}
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34 -Like the microcircuit, the mesocircuit represents four layers of cortex, L2/3, L4, L5, and L6, each consisting of a population of excitatory neurons and a population of inhibitory neurons. External input can be provided by a thalamic population TC.
35 -
36 -The mesocircuit is a spatially structured network model covering 4x4 mm² of cortical surface area which is similar in size to multi-electrode arrays in use today.
37 -
38 -The neurons of each population are assigned random positions in 2-dimensional layers and they are connected with distance-dependent connection probabilities and conduction delays.
39 -
40 -The densities of neurons and local synapses in the network are assumed to be realistic, amounting to ~~1.2 million neurons and ~~5.5 billion synapses.
41 -
42 -The model accounts for both spiking activity simulated with [[NEST>>https://www.nest-simulator.org]] and local-field potentials relying on [[LFPy>>https://LFPy.rtfd.io]].
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44 -(% class="row" id="HStatusofmodeldevelopment" %)
45 -= Status of model development =
46 -
47 -The mesocircuit is still under development and the neither the code nor a peer-reviewed manuscript have been published, yet.
48 -
49 -To date, only a [[preprint>>https://arxiv.org/abs/1805.10235]] with detailed model documentation and preliminary results is available on ArXiv.
50 -
51 -The Drive of this Collab provides access to a [[recent version of the model implementation>>https://wiki.ebrains.eu/bin/view/Collabs/mesocircuit/Drive]].
52 -
53 -The development of the mesocircuit model belongs to task "T4.2.1 - Spiking mesoscale cortical models with spatial organization" and constitutes the [[component C2418>>https://plus.humanbrainproject.eu/components/2418]].
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mesocircuit_sketch.png
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Mesocircuit